Karen Antebi is a former Mexican trade negotiator and diplomat who chairs the international practice at Prime Policy Group. With over 20 years of experience at the intersection of global trade, policy, and diplomacy, she is known for guiding clients through complex international challenges and advancing strategic priorities in Washington and beyond. Her cross-sector expertise and ability to build consensus across borders have made her a trusted advisor to global companies, industry coalitions, and government stakeholders.

Before joining Prime, Karen was Senior Director at IQOM Strategic Advisors, where she counseled multinational clients and advised Mexico’s largest private sector organization—representing 80% of the country’s GDP—on trade, regulatory, and investment issues. Previously, as Economic Counselor at the Embassy of Mexico in Washington, DC, she led the government’s U.S. outreach during the renegotiation of NAFTA into the USMCA and played a central role in resolving high-profile bilateral trade disputes.

Earlier in her career, Karen directed global compliance programs at BSA | The Software Alliance, engaging with U.S. and foreign governments on digital trade, cybersecurity, IP, and data policy. She began her public service in Mexico’s Ministry of Commerce as part of the original NAFTA negotiating team and later served as Chief of Staff to the Deputy Secretary for International Trade, contributing to Mexico’s free trade agreements with the EU, Israel, and Japan.

Karen holds a BA in Political Science from Brandeis University, a Master’s in International Policy Studies from Stanford University, and studied international relations at Somerville College, Oxford University. She is fluent in English and Spanish and conversant in French. Karen is married, has two children and lives in Washington, DC.

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