Karen Antebi is a Director and the International Practice Chair at Prime Policy Group, where she brings two decades of hands-on experience in international trade and government affairs. Known for her strategic leadership and advocacy across diverse sectors, Karen has built a reputation as an effective problem solver in both diplomatic and private sector arenas. Her expertise includes designing and executing regulatory and policy strategies that build consensus, resolve complex trade disputes, and advance business interests at the highest levels of government.

Before joining Prime, Karen served as Senior Director at IQOM Strategic Advisors, where she counseled multinational companies and advised the Mexican Business Council, Mexico’s largest private sector organization. This council represents 12 leading trade associations and accounts for 80% of Mexico's GDP. In this role, she provided strategic insights to support the country's major industries.

As Economic Counselor for the Trade and NAFTA Office at the Embassy of Mexico in Washington, D.C., Karen spearheaded the Mexican government’s outreach and advocacy efforts during the renegotiation of the North American Free Trade Agreement (NAFTA), which was successfully modernized and rebranded as the USMCA. She also played a key role in resolving several high-profile bilateral trade disputes between Mexico and the U.S.

At BSA | The Software Alliance, Karen served as Director of Global Compliance Programs, engaging U.S. and international governments, business leaders, and trade associations to address cybersecurity risks and the benefits of software asset management. She also advocated for fair market access in government procurement, intellectual property protection, international trade, cybersecurity policies, STEM education, and immigration reform.

Karen's career began in Mexico’s Ministry of Commerce as a key member of Mexico's NAFTA negotiating team. She later became Chief of Staff to Mexico's Deputy Secretary of Commerce for International Trade, where she coordinated intergovernmental efforts to successfully negotiate and implement Mexico’s free trade agreements with the European Union, Israel, and Japan.

Karen holds a bachelor's degree in Political Science and Government from Brandeis University and a master's degree in International Policy Studies and Political Economy from Stanford University. Fluent in both English and Spanish, she resides in Washington, D.C., with her husband, William.